BDBM10572 (3S)-3-{[5-(dimethylsulfamoyl)pyridin-3-yl]formamido}-5-{[(4-fluorophenyl)methyl]sulfanyl}-4-oxopentanoic acid::nicotinyl aspartyl ketone 27

SMILES CN(C)S(=O)(=O)c1cncc(c1)C(=O)N[C@@H](CC(O)=O)C(=O)CSCc1ccc(F)cc1

InChI Key InChIKey=GUBGLTVYUMWIIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10572   

TargetCaspase-3(Human)
Merck Frosst Canada

LigandPNGBDBM10572((3S)-3-{[5-(dimethylsulfamoyl)pyridin-3-yl]formami...)
Affinity DataIC50: 300nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed