BDBM10570 (3S)-3-({5-[ethyl(propan-2-yl)carbamoyl]pyridin-3-yl}formamido)-5-{[(4-fluorophenyl)methyl]sulfanyl}-4-oxopentanoic acid::nicotinyl aspartyl ketone 22

SMILES CCN(C(C)C)C(=O)c1cncc(c1)C(=O)N[C@@H](CC(O)=O)C(=O)CSCc1ccc(F)cc1

InChI Key InChIKey=MXVOFFJFKCZJSA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10570   

TargetCaspase-3(Human)
Merck Frosst Canada

LigandPNGBDBM10570((3S)-3-({5-[ethyl(propan-2-yl)carbamoyl]pyridin-3-...)
Affinity DataIC50: 250nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed