BDBM105280 US8575203, I-47

SMILES CCN1CC[C@H](Nc2cnc3ccc(cc3n2)C#CCNC(=O)c2cncn(Cc3ccc(F)c(F)c3)c2=O)[C@H](F)C1

InChI Key InChIKey=UTXWYFKDJYVHIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105280   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM105280(US8575203, I-47)
Affinity DataIC50: 4nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent