BDBM105252 US8575203, 297::US8575203, I-19/I-20

SMILES CN1CCC(CC1)Nc1cnc2ccc(cc2n1)C#CCNC(=O)c1cncn(Cc2ccc(F)c(F)c2)c1=O

InChI Key InChIKey=TYNNMYVYIJHKAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 105252   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM105252(US8575203, 297 | US8575203, I-19/I-20)
Affinity DataIC50: 4nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM105252(US8575203, 297 | US8575203, I-19/I-20)
Affinity DataIC50: 4nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent