BDBM105231 US8580800, 23

SMILES CN(C)C(=O)CN1[C@@H](C2=C(CN(C)NC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N

InChI Key InChIKey=AFCCCNBAOWYDCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105231   

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM105231(US8580800, 23)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent