BDBM105230 US8580800, 17

SMILES CCN1CC2=C([C@H](NC(=O)N2c2cccc(c2)C(F)(F)F)c2ccc(cc2)C#N)C(=O)N1

InChI Key InChIKey=ITWAOGDJFMKGEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105230   

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM105230(US8580800, 17)
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent