BDBM105159 CHEMBL2152709::US8569281, 196

SMILES Cc1[nH]nc2ccnc(OC3CCCC3)c12

InChI Key InChIKey=HGALVNDKPMQZCT-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 105159   

LigandPNGBDBM105159(CHEMBL2152709 | US8569281, 196)
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in baculovirus expression system by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM105159(CHEMBL2152709 | US8569281, 196)
Affinity DataKi:  858nMAssay Description:Binding affinity to LRRK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM105159(CHEMBL2152709 | US8569281, 196)
Affinity DataKi:  858nMAssay Description:This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining Kiapp, IC50 or percent inhibition values.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent