BDBM104968 US8569306, 5

SMILES CS(=O)(=O)CCCOc1cccn2c(cnc12)-c1ccnc(N[C@H]2CC[C@@H](CC2)C(=O)N2CCC(O)CC2)n1

InChI Key InChIKey=LZXLRJRSBFKIPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 104968   

TargetMitogen-activated protein kinase 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM104968(US8569306, 5)
Affinity DataIC50: 21.6nMpH: 7.5 T: 2°CAssay Description:Inhibition assay using JNK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 9(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM104968(US8569306, 5)
Affinity DataIC50: 50.3nMpH: 7.5 T: 2°CAssay Description:Inhibition assay using JNK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent