BDBM104908 CHEMBL468270::US8569313, Inhibitor 16

SMILES NCCCCc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1

InChI Key InChIKey=WAFSHTVICTUASP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 104908   

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM104908(CHEMBL468270 | US8569313, Inhibitor 16)
Affinity DataKi:  0.740nMAssay Description:Inhibition assay using matriptase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM104908(CHEMBL468270 | US8569313, Inhibitor 16)
Affinity DataKi:  1nMAssay Description:Inhibition of matriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM104908(CHEMBL468270 | US8569313, Inhibitor 16)
Affinity DataKi:  200nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM104908(CHEMBL468270 | US8569313, Inhibitor 16)
Affinity DataKi:  460nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM104908(CHEMBL468270 | US8569313, Inhibitor 16)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM104908(CHEMBL468270 | US8569313, Inhibitor 16)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed