BDBM104829 US8569314, 90

SMILES CCOC(=O)C1=C(C)N(c2nccn2[C@@H]1c1ccc(cc1)C#N)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=JHIVXCHUXFMPOR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104829   

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM104829(US8569314, 90)
Affinity DataIC50: 6.5nMAssay Description:In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
US Patent