BDBM10470 Bis-THA inhibitor 1d::Bis-THA inhibitor 9::CHEMBL386423::N-[10-(1,2,3,4-tetrahydroacridin-9-ylamino)decyl]-1,2,3,4-tetrahydroacridin-9-amine

SMILES C(CCCCCNc1c2CCCCc2nc2ccccc12)CCCCNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=CRXRFHPFIFVXJP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 10470   

TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandPNGBDBM10470(CHEMBL386423 | Bis-THA inhibitor 9 | N-[10-(1,2,3,...)
Affinity DataIC50: 3.10nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandPNGBDBM10470(CHEMBL386423 | Bis-THA inhibitor 9 | N-[10-(1,2,3,...)
Affinity DataIC50: 440nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandPNGBDBM10470(CHEMBL386423 | Bis-THA inhibitor 9 | N-[10-(1,2,3,...)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandPNGBDBM10470(CHEMBL386423 | Bis-THA inhibitor 9 | N-[10-(1,2,3,...)
Affinity DataIC50: 167nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandPNGBDBM10470(CHEMBL386423 | Bis-THA inhibitor 9 | N-[10-(1,2,3,...)
Affinity DataIC50: 167nMAssay Description:Inhibition of rat serum BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandPNGBDBM10470(CHEMBL386423 | Bis-THA inhibitor 9 | N-[10-(1,2,3,...)
Affinity DataIC50: 40nMAssay Description:Inhibition of rat brain AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed