BDBM10465 Bivalent 4-Aminopyridine 12k::bis((2R,3R)-2,3-dihydroxybutanedioic acid); N-[12-(pyridin-4-ylamino)dodecyl]pyridin-4-amine

SMILES C(CCCCCCNc1ccncc1)CCCCCNc1ccncc1

InChI Key InChIKey=REGVEKPXUMXNPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10465   

TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM10465(bis((2R,3R)-2,3-dihydroxybutanedioic acid); N-[12-...)
Affinity DataIC50: 403nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM10465(bis((2R,3R)-2,3-dihydroxybutanedioic acid); N-[12-...)
Affinity DataIC50: 1.44E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed