BDBM104486 US8586597, 101::USRE44599, 117

SMILES CC[C@H](Nc1ncnc2nc[nH]c12)c1nc2cccc(Cl)c2c(=O)n1-c1cc(F)cc(F)c1

InChI Key InChIKey=TWLUHIZKDUPYPV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 104486   

LigandPNGBDBM104486(US8586597, 101 | USRE44599, 117)
Affinity DataIC50: 12nMAssay Description:Compounds of the invention were tested for inhibitory activity and potency against PI3Kδ.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent

LigandPNGBDBM104486(US8586597, 101 | USRE44599, 117)
Affinity DataIC50: 12nMAssay Description:Biochemical assay using PI3K delta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
US Patent

LigandPNGBDBM104486(US8586597, 101 | USRE44599, 117)
Affinity DataIC50: 45nMAssay Description:Inhibition of human PI3K-delta using PIP2 as substrate in presence of gamma[32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed