BDBM104213 US8575145, 120::US8575145, 121::US8575145, 150::US8575145, 151::US8575145, 90::US8575145, 91

SMILES FC1CCNCCC1Oc1cc(F)cc2ccc(nc12)-c1nnc2ccccn12

InChI Key InChIKey=SJVQOMGMHYJTEW-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 104213   

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 30.5nMAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 131nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 39nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 959nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 520nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 10.9nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM104213(US8575145, 90 | US8575145, 91 | US8575145, 150 | U...)
Affinity DataIC50: 16.1nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent