BDBM104175 US8575145, 157::US8575145, 158::US8575145, 52/127/128

SMILES C1CNCCC(C1)Oc1cccc2ccc(nc12)-c1nnc2ccccn12

InChI Key InChIKey=FMCHSBJRGSMUTQ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 104175   

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104175(US8575145, 157 | US8575145, 158 | US8575145, 52/12...)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104175(US8575145, 157 | US8575145, 158 | US8575145, 52/12...)
Affinity DataIC50: 4.80nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104175(US8575145, 157 | US8575145, 158 | US8575145, 52/12...)
Affinity DataIC50: 19.1nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104175(US8575145, 157 | US8575145, 158 | US8575145, 52/12...)
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104175(US8575145, 157 | US8575145, 158 | US8575145, 52/12...)
Affinity DataIC50: 438nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104175(US8575145, 157 | US8575145, 158 | US8575145, 52/12...)
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM104175(US8575145, 157 | US8575145, 158 | US8575145, 52/12...)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM104175(US8575145, 157 | US8575145, 158 | US8575145, 52/12...)
Affinity DataIC50: 6.80nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM104175(US8575145, 157 | US8575145, 158 | US8575145, 52/12...)
Affinity DataIC50: 79.4nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent