BDBM10414 (1S,12S,14R)-4-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butyl]-14-hydroxy-9-methoxy-11-oxa-4-azatetracyclo[8.6.1.0^{1,12}.0^{6,17}]heptadeca-4,6(17),7,9,15-pentaen-4-ium; 2,2,2-trifluoroacetate::9-Dehydro-10-N-demethyl-10-N-(4-phthalimidobutyl)-galanthaminium trifluoroacetate::galanthamine deriv. 4b

SMILES COc1ccc2C=[N+](CCCCN3C(=O)c4ccccc4C3=O)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24

InChI Key InChIKey=SFRCWNPEMMNXAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10414   

TargetAcetylcholinesterase(Pacific electric ray)
Cnrs

LigandPNGBDBM10414(9-Dehydro-10-N-demethyl-10-N-(4-phthalimidobutyl)-...)
Affinity DataIC50: 470nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed