BDBM10408 (1S,12S,14R)-14-hydroxy-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0^{1,12}.0^{6,17}]heptadeca-4,6,8,10(17),15-pentaen-4-ium::Galanthamine derivative 5::galanthamine deriv. 14

SMILES COc1ccc2C=[N+](C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24

InChI Key InChIKey=RKYCDHLWOSUDFI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10408   

TargetAcetylcholinesterase(Pacific electric ray)
Weizmann Institute of Science

LigandPNGBDBM10408(galanthamine deriv. 14 | (1S,12S,14R)-14-hydroxy-9...)
Affinity DataIC50: 702nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Weizmann Institute of Science

LigandPNGBDBM10408(galanthamine deriv. 14 | (1S,12S,14R)-14-hydroxy-9...)
Affinity DataIC50: 266nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Weizmann Institute of Science

LigandPNGBDBM10408(galanthamine deriv. 14 | (1S,12S,14R)-14-hydroxy-9...)
Affinity DataIC50: 140nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed