BDBM103942 US10399973, Example 17::US8569338, 24::US9035066, 17::US9493457, 17::US9890160, Example 17

SMILES CC(C)C1N(CCc2nc[nH]c12)C(=O)OCC1CCOC1

InChI Key InChIKey=YYEWOALXGQHVJR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 103942   

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM103942(US8569338, 24 | US9493457, 17 | US9035066, 17 | US...)
Affinity DataIC50: 91nMT: 2°CAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. The enzyme activity was measured with benzylamine as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM103942(US8569338, 24 | US9493457, 17 | US9035066, 17 | US...)
Affinity DataIC50: 91nMpH: 7.4Assay Description:Briefly, test compounds were dissolved in dimethyl sulfoxide (DMSO) to a concentration of 10 mM. Dose-response measurements were assayed by either cr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2015
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM103942(US8569338, 24 | US9493457, 17 | US9035066, 17 | US...)
Affinity DataIC50: 91nMpH: 7.4Assay Description:Briefly, test compounds were dissolved in dimethyl sulfoxide (DMSO) to a concentration of 10 mM. Dose-response measurements were assayed by either cr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM103942(US8569338, 24 | US9493457, 17 | US9035066, 17 | US...)
Affinity DataIC50: 91nMAssay Description:Briefly, test compounds were dissolved in dimethyl sulfoxide (DMSO) to a concentration of 10 mM. Dose-response measurements were assayed by either cr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM103942(US8569338, 24 | US9493457, 17 | US9035066, 17 | US...)
Affinity DataIC50: 91nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent