BDBM103928 US8569511, 12

SMILES O=C(NC1CC1)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1

InChI Key InChIKey=ZZTUTRWGPCSZAS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 103928   

Target3-phosphoinositide-dependent protein kinase 1(Human)
University of Utah

US Patent
LigandPNGBDBM103928(US8569511, 12)
Affinity DataIC50: 1.16E+4nMAssay Description:The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
University of Utah

US Patent
LigandPNGBDBM103928(US8569511, 12)
Affinity DataIC50: 920nMAssay Description:The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
University of Utah

US Patent
LigandPNGBDBM103928(US8569511, 12)
Affinity DataIC50: 900nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed