BDBM103910 JNK3 inhibitor 7::US8562945, 243

SMILES CN1C=C[N]2=C1C[N]1(CCc3ccc(SOON)cc3)CC3=[N](C=CN3C)[Re+]21

InChI Key InChIKey=

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 103910   

TargetCarbonic anhydrase 9(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103910(JNK3 inhibitor 7 | US8562945, 243)
Affinity DataIC50: 564nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

TargetCarbonic anhydrase 2(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103910(JNK3 inhibitor 7 | US8562945, 243)
Affinity DataIC50: 652nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute

LigandPNGBDBM103910(JNK3 inhibitor 7 | US8562945, 243)
Affinity DataIC50: 127nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
The Scripps Research Institute

LigandPNGBDBM103910(JNK3 inhibitor 7 | US8562945, 243)
Affinity DataIC50: 155nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed