BDBM103895 US10047086, 9::US10640503, Example 9::US9695168, 9

SMILES CCC1CCC(=CC1)c1c(cc(OC[C@@H]2CCNC2)c2cncn12)-c1ccc(cc1)C#N

InChI Key InChIKey=DEVZUBUTQMCALT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 103895   

LigandPNGBDBM103895(US9695168, 9 | US10047086, 9 | US10640503, Example...)
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:LANCE LSD1/KDM1A demethylase assay 10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM103895(US9695168, 9 | US10047086, 9 | US10640503, Example...)
Affinity DataIC50: 50nMpH: 7.5Assay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM103895(US9695168, 9 | US10047086, 9 | US10640503, Example...)
Affinity DataIC50: 50nMAssay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent