BDBM103872 US9695165, 55

SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1cc2cnc(nc2n(C2CCCC2)c1=O)-c1ccc2OCCN(C(=O)C=C)c2c1

InChI Key InChIKey=ZDKUJQCFFHNECN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103872   

TargetFibroblast growth factor receptor 4(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM103872(US9695165, 55)
Affinity DataIC50: 55nMpH: 7.5 T: 2°CAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
Go to US Patent