BDBM103765 US8551978, I-34::US8816088, I-34::US9682957, I-34

SMILES CN(C(=O)CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1)c1cccc(c1)C(=O)Nc1ccc(CCNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)cc1

InChI Key InChIKey=SVZCFOOBMRCIIT-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 103765   

TargetBeta-2 adrenergic receptor(Human)
Theravance Respiratory

US Patent
LigandPNGBDBM103765(US8816088, I-34 | US8551978, I-34 | US9682957, I-3...)
Affinity DataEC50:  1nMT: 2°CAssay Description:cAMP assays were performed in a radioimmunoassay format using the Flashplate Adenylyl Cyclase Activation Assay System with [125I]-cAMP (NEN SMP004, P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
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TargetMuscarinic acetylcholine receptor M3(Human)
Theravance

US Patent
LigandPNGBDBM103765(US8816088, I-34 | US8551978, I-34 | US9682957, I-3...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assay using muscarinic receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2014
Entry Details
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TargetMuscarinic acetylcholine receptor M3(Human)
Theravance

US Patent
LigandPNGBDBM103765(US8816088, I-34 | US8551978, I-34 | US9682957, I-3...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assays for cloned muscarinic receptors were performed in 96-well microtiter plates in a total assay volume of 100 uL. CHO cell me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Theravance

US Patent
LigandPNGBDBM103765(US8816088, I-34 | US8551978, I-34 | US9682957, I-3...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assays for cloned muscarinic receptors were performed in 96-well microtiter plates in a total assay volume of 100 μL. CHO ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent