BDBM103507 CHEMBL2172187::US8552017, 1.1(4).HCl

SMILES CNc1nn2c3CCN(C)Cc3c(C)nc2c1S(=O)(=O)c1ccccc1

InChI Key InChIKey=GLGRPQPRAVVCRJ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103507   

Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM103507(CHEMBL2172187 | US8552017, 1.1(4).HCl)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]lysergic acid diethylamide from human recombinant 5HT6 receptor expressed in HeLa cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM103507(CHEMBL2172187 | US8552017, 1.1(4).HCl)
Affinity DataKi:  0.685nM IC50: 1.48nMAssay Description:The screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out b the method of radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
Go to US Patent