BDBM103486 US8552004, 5.06

SMILES CNc1nc2ccc(F)cc2n1-c1nc(cc(n1)C(C)(C)[S@@](C)(=N)=O)N1CCOC[C@H]1C

InChI Key InChIKey=PSIPSQLSHTYKJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103486   

TargetSerine/threonine-protein kinase ATR(Human)
Astrazeneca

US Patent
LigandPNGBDBM103486(US8552004, 5.06)
Affinity DataIC50: 44.4nMAssay Description:ATM and ATR have distinct and overlapping responses to DNA damage. They must participate together and responses must be co-ordinated. Both pathways...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
Go to US Patent