BDBM103483 US8552004, 3.02

SMILES CNc1cc2c(cncc2[nH]1)-c1nc(cc(n1)C(C)(C)[S@](C)(=N)=O)N1CCOC[C@H]1C

InChI Key InChIKey=LNTYIKIHBXWTDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103483   

TargetSerine/threonine-protein kinase ATR(Human)
Astrazeneca

US Patent
LigandPNGBDBM103483(US8552004, 3.02)
Affinity DataIC50: 8.43nMAssay Description:ATM and ATR have distinct and overlapping responses to DNA damage. They must participate together and responses must be co-ordinated. Both pathways...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
Go to US Patent