BDBM103474 US8552004, 4.03

SMILES C[C@@H]1COCCN1c1cc(nc(n1)-c1cccc2[nH]ccc12)C1(CCOCC1)[S@@](C)(=N)=O

InChI Key InChIKey=IFKRIACODANJFM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103474   

TargetSerine/threonine-protein kinase ATR(Human)
Astrazeneca

US Patent
LigandPNGBDBM103474(US8552004, 4.03)
Affinity DataIC50: 51.1nMAssay Description:ATM and ATR have distinct and overlapping responses to DNA damage. They must participate together and responses must be co-ordinated. Both pathways...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
Go to US Patent