BDBM103444 US8552037, 91

SMILES CC(=O)NCC[C@H]1CCc2ccc3nc(C)oc3c12

InChI Key InChIKey=CCRUCMHMQXUZAT-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 103444   

TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM103444(US8552037, 91)
Affinity DataIC50: 15nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetMelatonin receptor type 1B(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM103444(US8552037, 91)
Affinity DataIC50: 9.60nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetMelatonin receptor type 1B(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM103444(US8552037, 91)
Affinity DataKi:  6.10nMAssay Description:Displacement of 2-[125l]-lodomelatonin from human MT2 expressed in CHO cell membrane incubated for 150 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM103444(US8552037, 91)
Affinity DataKi:  23nMAssay Description:Displacement of 2-[125l]-lodomelatonin from human MT1 expressed in CHO cell membrane incubated for 150 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed