BDBM10300 1-methyl-2,3-dioxo-2,3-dihydro-1H-indole-5-carboxylate::Isatin analog 4

SMILES CN1C(=O)C(=O)c2cc(ccc12)C([O-])=O

InChI Key InChIKey=ROPLRWWORDJINQ-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10300   

TargetCaspase-3(Human)
Glaxosmithkline

LigandPNGBDBM10300(1-methyl-2,3-dioxo-2,3-dihydro-1H-indole-5-carboxy...)
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2006
Entry Details Article
PubMed