BDBM10299 5-Nitroisatin::5-nitro-2,3-dihydro-1H-indole-2,3-dione::Isatin analog 3

SMILES O=C1Nc2ccc(cc2C1=O)N(=O)=O

InChI Key InChIKey=UNMYHYODJHKLOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10299   

TargetCaspase-3(Human)
Glaxosmithkline

LigandPNGBDBM10299(5-nitro-2,3-dihydro-1H-indole-2,3-dione | 5-Nitroi...)
Affinity DataIC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2006
Entry Details Article
PubMed