BDBM102903 US8541572, 569

SMILES COc1ccc2CN(CC3(NC(=O)NC3=O)C#Cc3ccc(cc3)N=C(NC#N)NC3CC3)C(=O)c2c1

InChI Key InChIKey=JHQDPOJGNRKTCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 102903   

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102903(US8541572, 569)
Affinity DataIC50: 268nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
Go to US Patent