BDBM102897 US8541572, 563

SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3cccnc3-c3ccncc3)C(=O)c2c1

InChI Key InChIKey=ZHIVPINNYKAVCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 102897   

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102897(US8541572, 563)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
Go to US Patent