BDBM102720 US8541572, 1311

SMILES CCN1CCN(C(N=O)c2ccc(cc2F)C#C[C@]2(CN3Cc4ccc(OC)c(F)c4C3=O)NC(=O)NC2=O)[C@@H](C)C1

InChI Key InChIKey=OCBISIUSASRRNI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 102720   

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102720(US8541572, 1311)
Affinity DataKi:  0.180nM IC50: 69nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
Go to US Patent