BDBM102592 US8536172, I-41

SMILES CC(=O)N1CCN(CC1)c1cccc2n(ccc12)-c1ccnc(N[C@H]2CC[C@H](CS(C)(=O)=O)CC2)n1

InChI Key InChIKey=NQDDYGCYNZIMTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102592   

TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM102592(US8536172, I-41)
Affinity DataIC50: 25nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM102592(US8536172, I-41)
Affinity DataIC50: 164nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
Go to US Patent