BDBM101911 US9695163, 30

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1C1(CC1)C#N)c1csc(n1)C(C)(C)O

InChI Key InChIKey=CPVDJFKMVPOBEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101911   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM101911(US9695163, 30)
Affinity DataIC50: 13nMT: 2°CAssay Description:Briefly, for intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the orexin-1 receptor (e.g., rat or human) or the orexi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
Go to US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM101911(US9695163, 30)
Affinity DataIC50: 1.20E+3nMT: 2°CAssay Description:Briefly, for intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the orexin-1 receptor (e.g., rat or human) or the orexi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
Go to US Patent