BDBM101470 US8524710, 48

SMILES FC(F)(F)c1cc(nc(n1)C#N)N1CC[C@@H](C1)S(=O)(=O)c1ccc(cc1Cl)N1CCN(CC1)C1CC1

InChI Key InChIKey=XLHJNAUYMFOCEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101470   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM101470(US8524710, 48)
Affinity DataIC50: 0.0560nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2013
Entry Details
Go to US Patent

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM101470(US8524710, 48)
Affinity DataIC50: 5.60nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2013
Entry Details
Go to US Patent