BDBM101457 US8524710, 35

SMILES Fc1ccc(CNC(=O)[C@@H]2C[C@@H](CN2c2ccnc(n2)C#N)S(=O)(=O)c2ccccc2C(F)(F)F)cc1

InChI Key InChIKey=GUURLPWFKJDGNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101457   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM101457(US8524710, 35)
Affinity DataIC50: 2.30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2013
Entry Details
Go to US Patent