BDBM10143 lysine sulfonamide analogue 7::methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-6-hydroxyhexyl]carbamoyl}-3-phenylpropyl]carbamate

SMILES COC(=O)N[C@@H](CCc1ccccc1)C(=O)NCCCCC(CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1

InChI Key InChIKey=UVGUQZBWIDVZMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10143   

TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10143(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 40nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed