BDBM10142 lysine sulfonamide analogue 6::methyl N-[(S)-{[(5R)-5-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-6-hydroxyhexyl]carbamoyl}(phenyl)methyl]carbamate

SMILES COC(=O)N[C@H](C(=O)NCCCCC(CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1)c1ccccc1

InChI Key InChIKey=WKQNFLURXJVQKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10142   

TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10142(methyl N-[(S)-{[(5R)-5-[(4-aminobenzene)(2-methylp...)
Affinity DataIC50: 300nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed