BDBM10130 9-fluoro-5-(1H-pyrrol-2-yl)-7-[(2R)-pyrrolidin-2-ylsulfanyl]-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(11),4,6,8(12),9-pentaen-3-one::trisubstituted naphthostyril analogue 8c

SMILES Fc1ccc2NC(=O)c3c(cc(S[C@@H]4CCCN4)c1c23)-c1ccc[nH]1

InChI Key InChIKey=CZPOLKWPNYHSGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10130   

LigandPNGBDBM10130(9-fluoro-5-(1H-pyrrol-2-yl)-7-[(2R)-pyrrolidin-2-y...)
Affinity DataIC50: 18nMAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
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Date in BDB:
6/27/2006
Entry Details Article
PubMed