BDBM100979 US8524909, 133::US8524909, 59

SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1COCC[C@H]1N1CCC2CC12)C(F)(F)F

InChI Key InChIKey=DTMDMRJPXFKKGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100979   

TargetSodium- and chloride-dependent glycine transporter 1(Bovine)
Hoffmann-La Roche

US Patent
LigandPNGBDBM100979(US8524909, 133 | US8524909, 59)
Affinity DataIC50: 114nMT: 2°CAssay Description:Glycine uptake inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2013
Entry Details
Go to US Patent

TargetSodium- and chloride-dependent glycine transporter 1(Bovine)
Hoffmann-La Roche

US Patent
LigandPNGBDBM100979(US8524909, 133 | US8524909, 59)
Affinity DataIC50: 26.4nMT: 2°CAssay Description:Glycine uptake inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2013
Entry Details
Go to US Patent