BDBM10074 (3Z)-5-fluoro-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one::C-5 substituted oxindole inhibitor 4b::oxindole inhibitor 1b

SMILES COc1cc[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12

InChI Key InChIKey=BDXDLMWAHSTBQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10074   

LigandPNGBDBM10074((3Z)-5-fluoro-3-[(3-methoxy-1H-pyrrol-2-yl)methyli...)
Affinity DataIC50: 847nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10074((3Z)-5-fluoro-3-[(3-methoxy-1H-pyrrol-2-yl)methyli...)
Affinity DataIC50: 847nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed