BDBM100359 US10383835, Compound 4b::US11123311, Compound 4b::US12251379, Compound 4b::US8501783, 1122

SMILES CCCN1CCC(CNC(=O)NC23CC4CC(CC(C4)C2)C3)CC1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 100359   

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM100359(US8501783, 1122 | US10383835, Compound 4b | US1112...)
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
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TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM100359(US8501783, 1122 | US10383835, Compound 4b | US1112...)
Affinity DataIC50: 2.60E+3nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
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TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandPNGBDBM100359(US8501783, 1122 | US10383835, Compound 4b | US1112...)
Affinity DataIC50: 2.60E+3nMAssay Description:Any of a number of standard assays for determining epoxide hydrolase activity can be used to determine inhibition of sEH. For example, suitable assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
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TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandPNGBDBM100359(US8501783, 1122 | US10383835, Compound 4b | US1112...)
Affinity DataIC50: 2.60E+3nMAssay Description:Suitable in vitro assays are described in Zeldin et al., J Biol. Chem. 268:6402-6407 (1993). Suitable in vivo assays are described in Zeldin et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
Go to US Patent