BDBM86642 BC11-38::US9173884, BC11-38

SMILES CCCSc1nc2CCSc2c(=O)n1-c1ccccc1

InChI Key InChIKey=YHNDCCKFNWDQGW-UHFFFAOYSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 86642   

LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant PDE11More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 280nMAssay Description:Inhibition of PDE11A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 280nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 280nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed