BDBM50478376 BB-78485::CHEMBL261713

SMILES ONC(=O)[C@@H](Cc1ccc2ccccc2c1)NS(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=MMOUXLMPQFMDRD-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50478376   

TargetMatrix metalloproteinase-9(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50478376(BB-78485 | CHEMBL261713)
Affinity DataIC50: 97nMAssay Description:Inhibition of human MMP-9 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50478376(BB-78485 | CHEMBL261713)
Affinity DataIC50: 416nMAssay Description:Inhibition of human MMP-3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50478376(BB-78485 | CHEMBL261713)
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-2 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli (strain K12))
Duke University Medical Center

Curated by ChEMBL
LigandPNGBDBM50478376(BB-78485 | CHEMBL261713)
Affinity DataKi:  0.0690nMAssay Description:Inhibition of Escherichia coli LpxCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli (strain K12))
Duke University Medical Center

Curated by ChEMBL
LigandPNGBDBM50478376(BB-78485 | CHEMBL261713)
Affinity DataKi:  0.0860nMAssay Description:Inhibition of Escherichia coli LpxC Q202W/G210S mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Rhizobium leguminosarum bv. trifolii (strain WSM13...)
Duke University Medical Center

Curated by ChEMBL
LigandPNGBDBM50478376(BB-78485 | CHEMBL261713)
Affinity DataKi:  0.700nMAssay Description:Inhibition of Rhizobium leguminosarum LpxC W206Q/S214G mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli (strain K12))
Duke University Medical Center

Curated by ChEMBL
LigandPNGBDBM50478376(BB-78485 | CHEMBL261713)
Affinity DataKi:  20nMAssay Description:Inhibition of Escherichia coli LpxCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed