BDBM50312667 (R)-1-(2-chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1H-pyrazolo[3,4-d]pyrimidine-4(5H)-one::BAY73-6691::CHEMBL1098370

SMILES C[C@H](CC1=NC(=O)C2C=NN(C2N1)c1ccccc1Cl)C(F)(F)F

InChI Key InChIKey=JPHHGFNKNXDZSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312667   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50312667(BAY73-6691 | (R)-1-(2-chlorophenyl)-6-(3,3,3-trifl...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human PDE9A expressed in Escherichia coli BL21 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed