BDBM50632668 BAY-294

SMILES CNCc1ccccc1-c1csc(c1)[C@H](C)Nc1nc(C)nc2cc(OC)c(OC)cc12

InChI Key InChIKey=WEGLOYDTDILXDA-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50632668   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of SOS1/KRAS (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 2.34E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 3.91E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 4.04E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 1.89E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 2.34E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 2.34E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGuanine nucleotide exchange factor DBS(Homo sapiens)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 4.12E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 1.86E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 4.57E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed