BDBM50101979 2,6-Dihydroxyanthraquinone::2,6-dihydroxy-9,10-anthracenedione::2,6-dihydroxy-9,10-anthraquinone::2,6-dihydroxyanthra-9,10-quinone::2,6-dihydroxyanthracene-9,10-dione::Az-F::CHEMBL298398::anthraflavic acid::anthraflavin

SMILES Oc1ccc2C(=O)c3cc(O)ccc3C(=O)c2c1

InChI Key InChIKey=APAJFZPFBHMFQR-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50101979   

TargetEstrogen receptor beta(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-dihydroxyanthracene-9,10-dione | anthraflavin ...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of binding of 17 beta-estradiol to human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-dihydroxyanthracene-9,10-dione | anthraflavin ...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-dihydroxyanthracene-9,10-dione | anthraflavin ...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-dihydroxyanthracene-9,10-dione | anthraflavin ...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of binding of 17 beta-estradiol to human Estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-dihydroxyanthracene-9,10-dione | anthraflavin ...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-dihydroxyanthracene-9,10-dione | anthraflavin ...)
Affinity DataIC50: 5.62E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-dihydroxyanthracene-9,10-dione | anthraflavin ...)
Affinity DataKi:  310nMAssay Description:Inhibition of binding of 17 beta-estradiol to human Estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-dihydroxyanthracene-9,10-dione | anthraflavin ...)
Affinity DataKi:  690nMAssay Description:Inhibition of binding of 17 beta-estradiol to human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed