BDBM50242053 6,8-didec-(1Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-indolizinium trifluoroacetic acid salt::Anibamine::CHEMBL2057533::CHEMBL469649::anibamine TFA

SMILES CCCCCCCC\C=C/c1c2CCC[n+]2c(C)c(\C=C/CCCCCCCC)c1C

InChI Key InChIKey=LOTZSYKJMYSNJV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50242053   

TargetC-C chemokine receptor type 5(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50242053(CHEMBL2057533 | 6,8-didec-(1Z)-enyl-5,7-dimethyl-2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-gp120 from human CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50242053(CHEMBL2057533 | 6,8-didec-(1Z)-enyl-5,7-dimethyl-2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]gp-120 from human CCR5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50242053(CHEMBL2057533 | 6,8-didec-(1Z)-enyl-5,7-dimethyl-2...)
Affinity DataIC50: 5.43E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in MOLT4/CCR5 cells assessed as inhibition of CCL5-induced intracellular calcium mobilization by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50242053(CHEMBL2057533 | 6,8-didec-(1Z)-enyl-5,7-dimethyl-2...)
Affinity DataIC50: 5.40E+3nMAssay Description:Antagonist activity at CCR5 receptor expressed in human MOLT4 cells assessed as inhibition of CCl5-induced calcium mobilization after 1 hr by Fluor-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50242053(CHEMBL2057533 | 6,8-didec-(1Z)-enyl-5,7-dimethyl-2...)
Affinity DataIC50: 5.40E+3nMAssay Description:Antagonist activity at CCR5 receptor in human MOLT4 cells assessed as inhibition of chemokine-induced calcium mobilization using Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed