BDBM50479267 Alternariol::CHEBI:64983

SMILES Cc1cc(O)cc2oc(=O)c3c(O)cc(O)cc3c12

InChI Key InChIKey=CEBXXEKPIIDJHL-UHFFFAOYSA-N

Data  29 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50479267   

TargetSerine/threonine-protein kinase B-raf(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 6.19E+3nMAssay Description:Inhibition of recombinant B-RAF-V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 707nMAssay Description:Inhibition of CLK2 (unknown origin) incubated for 60 mins by ADP-Glo reagent based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetEphrin type-B receptor 4(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of recombinant EPHB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of recombinant CDK2/CycAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of recombinant IGF1R phosphorylation transfected in mouse embryonic fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.09E+4nMAssay Description:Inhibition of recombinant COTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of recombinant VEGFR2 phosphorylation in human HUE cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 9.29E+3nMAssay Description:Inhibition of recombinant FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.44E+3nMAssay Description:Inhibition of recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 5.03E+3nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of recombinant TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of recombinant EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of recombinant Aurora B phosphorylation in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of recombinant ARK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of recombinant AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of recombinant ERBB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 9.29E+3nMAssay Description:Inhibition of recombinant CDK4/CycD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 7.74E+3nMAssay Description:Inhibition of recombinant CK2alpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of recombinant PLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 8.13E+3nMAssay Description:Inhibition of recombinant INSRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of recombinant IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of recombinant FLT3 phosphorylation transfected in mouse embryonic fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed